Contrast Sensitivity and Eye Drops英文文献资料.docVIP

Open Journal of Ophthalmology, 2012, 2, 60-63 /10.4236/ojoph.2012.23013 Published Online August 2012 (http://www.SciRP.org/journal/ojoph) Contrast Sensitivity and Eye Drops Theodosios Chatzibalis , Konstantinos Stamoulas , Athanasios Karamitsos , Diamantis Almaliotis , 1 1 1 1 2 3 1 Vasiliki Mirtsou-Fidani , Nikolaos Georgiadis , Vasileios Karampatakis 1 Laboratory of Experimental Ophthalmology, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece; Laboratory 2 of Pharmacology, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece; 1st Eye Clinic, Medical School, Aris- totle University of Thessaloniki, Thessaloniki, Greece. 3 Email: almaliotis_diamantis@yahoo.gr Received March 13 , 2012; revised April 16 , 2012; accepted May 10 , 2012 th th th ABSTRACT Purpose: To evaluate the influence of commonly used eye drops on contrast sensitivity (CS). Design: Prospective study. Participants: One hundred twenty volunteers were enrolled. Methods: The CS of ophthalmologically healthy indi- viduals was evaluated at baseline examination before the instillation, 20 and 40 minutes after the instillation of di- clofenac sodium and commonly used anti-glaucoma eye drops (latanoprost, brimonidine tartrate, combination of dor- zolamide hydrochloride and timolol maleate). CS was assessed at 7 spatial frequencies varying from 1.5 c/d to 20 c/d by the use of Mentor B-VAT II-SG video acuity tester. Results: Diclofenac sodium induced a mild, however statistically significant decrease on