体检人员血尿酸与代谢综合征组分的关系.pdfVIP

( ) 20095 305 381 ¹ º º º º ¹ 孙广慧 刘 颖 冷 松 赵 辉 梁慧文 苏本利 : 为观察血尿酸与代谢综合征(MS) 及其各组分 相关性, 随机检测MS ,调查人群血尿酸( SUA) 水平 865 份结果 显示: 体检 865 名人员 高尿酸血症患病率为 6. 6 % , 男性为10. 4% , 女性为 3. 2 % 与正常血尿酸组比较, 高血尿 酸组 BMIBPFPG 和血脂谱均升高( P 均 0.05) ;研究对象 SUA 水平与MS 危险因素呈显著相关, 其中与腰围 SBPDBPTGFPGHOM- I 呈正相关,与HDL- C 呈负相关; 随着代谢异常数目 增加,SUA 水平呈上升趋势; 多元 Logistic 回归高尿酸血症独立相关于超重高血压和血脂异常提示 SUA 水平与MS 危险因素密切相关; 高尿酸血症 独立相关于超重高血压和血脂异常 : 血尿酸,代谢综合征关系 : 589 : A : 1002- 0772(2009) 5- 0027- 02 Relationship between the P revalence of Serum Uric Acidconcentration with Metabolic Syndrome and Its Components S UN Guang-hui , L I U Ying , L EN G So ng , et al . Dep ar tment of Endocr inolog , the Second Af f iliated H o p ital of D alian Medi- cal Univ er ity , Dalian 116023, China Abstract:T o investigate the relationship of serum uric( SUA) concentration with components of matebolic syndrome( MS) . 865 subjects tested with metabolic syndromewas performed in adults aged 23- 75 years in out- patient department, levels of U A and lipid file were collected, hyperuricemia ( HUA ) prevalence and related parameters were detected. esults showed that the HU A prevalence was 6. 6%( Male in 10. 4%, Female in 3. 2%) . Subject s with HU A versus normal uric acid had the increased levels of BMI, BP, FPG and lipid profile( all P 0. 05) . Correlation analysis demonstrated that ser- um uric acid level was positively correlated with Body Mass Index (BMI) ( r = 0. 31, P 0. 01) , systolic BP( r = 0. 20, P 0.01) , diastolic BP( r = 0. 21, P 0. 01) , serum triglyceride ( r = 0. 29, P 0. 01) , fasting blood glucose( r= 0. 15, P 0.05) , as well as the number of M S components , and negatively correlated with high- densi