Regulation of Sulfotransferase and UDP-Glucuronosyltransferase Gene Expression by the PPARs 外文参考文献.docVIP

HindawiPublishingCorporation PPARResearch Volume2009,ArticleID728941,14pages doi:10.1155/2009/728941 ReviewArticle RegulationofSulfotransferaseandUDP-Glucuronosyltransferase GeneExpressionbythePPARs MelissaRunge-MorrisandThomasA.Kocarek InstituteofEnvironmentalHealthSciences,WayneStateUniversity,Detroit,MI48201,USA CorrespondenceshouldbeaddressedtoMelissaRunge-Morris,m.runge-morris@ Received20February2009;Accepted14April2009 RecommendedbyJohnY.L.Chiang During phase II metabolism, a substrate is rendered more hydrophilic through the covalent attachment of an endogenous molecule.Thecytosolicsu