ofphotoactiveyellowprotein.PDFVIP

Hydrogen bond dynamics in the active site of photoactive yellow protein Paul A. Sigala, Mark A. Tsuchida, and Daniel Herschlag1 Department of Biochemistry, Stanford University, Stanford, CA 94305-5307 Edited by Ann E. McDermott, Columbia University, New York, NY, and approved April 24, 2009 (received for review February 5, 2009) Hydrogen bonds play major roles in biological structure and function. higher-order functional roles within proteins is provided by the Nonetheless, hydrogen-bonded protons are not typically observed by cytosolic bacterial