Age Distribution of Cases of 2009 (H1N1) Pandemic Influenza in Comparison with Seasonal Influenza 英文参考文献.docVIP

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Age Distribution of Cases of 2009 (H1N1) Pandemic Influenza in Comparison with Seasonal Influenza 英文参考文献.doc

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Age Distribution of Cases of 2009 (H1N1) Pandemic Influenza in Comparison with Seasonal Influenza 英文参考文献

AgeDistributionofCasesof2009(H1N1)Pandemic InfluenzainComparisonwithSeasonalInfluenza DrososE.Karageorgopoulos1,EvridikiK.Vouloumanou1,IoannaP.Korbila1,AnastasiosKapaskelis1,2, MatthewE.Falagas1,2,3 * 1Alfa Institute of Biomedical Sciences (AIBS), Athens, Greece, 2Department of Medicine, Henry Dunant Hospital, Athens, Greece, 3Department of Medicine, Tufts UniversitySchoolofMedicine,Boston,Massachusetts,UnitedStatesofAmerica Abstract Introduction: Several aspects of the epidemiology of 2009 (H1N1) pandemic influenza have not been accurately determined.Wesoughttostudywhethertheagedistributionofcasesdiffersincomparisonwithseasonalinfluenza. Methods:Wesearched forofficial, publicly available data through theinternet from different countries worldwide on the age distribution of cases of influenza during the 2009 (H1N1) pandemic influenza period and most recent seasonal influenza periods. Data had to be recorded through the same surveillance system for both compared periods. Results: For 2009 pandemic influenza versus recent influenza seasons, in USA, visits for influenza-like illness to sentinel providers were more likely to involve the age groups of 5–24, 25–64 and 0–4 years compared with the reference group of .64 years [odds ratio (OR) (95% confidence interval (CI)): 2.43 (2.39–2.47), 1.66 (1.64–1.69), and 1.51 (1.48–1.54), respectively]. Pediatric deaths were less likely in the age groups of 2–4 and ,2 years than the reference group of 5–17 years [OR (95% CI): 0.46 (0.25–0.85) and 0.49 (0.30–0.81), respectively]. In Australia, notifications for laboratory-confirmed influenza were more likely inthe age groups of10–19, 5–9, 20–44, 45–64 and 0–4years than thereference group of.65years [OR(95% CI):7.19 (6.67–7.75), 5.33(4.90–5.79), 5.04(4.70–5.41), 3.12 (2.89–3.36) and 1.89 (1.75–2.05), respectively]. In New Zealand, consultations for influenza-like illness by sentinel providers were more likely in the age groups of ,1, 1–4, 35–49, 5–19, 20–34 and 50–64 years th