Association between Walking Speed and Age in Healthy, Free-Living Individuals Using Mobile Accelerometry—A Cross-Sectional Study 英文参考文献.docVIP

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Association between Walking Speed and Age in Healthy, Free-Living Individuals Using Mobile Accelerometry—A Cross-Sectional Study 英文参考文献.doc

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Association between Walking Speed and Age in Healthy, Free-Living Individuals Using Mobile Accelerometry—A Cross-Sectional Study 英文参考文献

AssociationbetweenWalkingSpeedandAgeinHealthy, Free-LivingIndividualsUsingMobileAccelerometry—A Cross-SectionalStudy MichaelaSchimpl1,2,CarmelMoore3,ChristianLederer1,AnnekeNeuhaus1,JenniferSambrook4 ,John Danesh3,WillemOuwehand4,MartinDaumer1,2* 1Sylvia Lawry Centre for Multiple Sclerosis Research e.V. – The Human Motion Institute, Munich, Germany, 2Trium Analysis Online GmbH, Munich, Germany, 3DepartmentofPublicHealthandPrimaryCare,UniversityofCambridge,Cambridge,UnitedKingdom,4DepartmentofHaematology,UniversityofCambridgeandNHS BloodandTransplant,Cambridge,UnitedKingdom Abstract Context: Walking speed is a fundamental parameter of human motion and is increasingly considered as an important indicatorofindividuals’healthstatus. Objective:Toevaluatetherelationshipofgaitparameters,anddemographicandphysicalcharacteristicsinhealthymen andwomen. Design,Setting,andParticipants:Recruitmentofasubsample(n=358)ofmaleandfemaleblooddonorstakingpartinthe CambridgeCardioResourcestudy.Collectionofdemographicdata,measurementofphysicalcharacteristics(height,weight andbloodpressure)andassessmentof7-day,free-livingactivityparametersusingaccelerometryandanovelalgorithmto measurewalkingspeed.Participantswereamedian(interquartilerange[IQR])ageof49(16)years;45%women;andhada median(IQR)BMIof26(5.4). MainOutcomeMeasure:Walkingspeed. Results:Inthisstudy,thehypothesisthatwalkingspeeddeclineswithagewasgeneratedusinganinitial‘open’dataset. Thiswassubsequentlyvalidatedinaseparate‘closed’datasetthatshowedadecreaseofwalkingspeedof20.0037m/sper year. This is equivalent toadifference of 1.2 minutes, when walking adistance of 1 kmaged 20 comparedto 60years. Associationsbetweenwalkingspeedandotherparticipantcharacteristics(i.e.gender,BMIandbloodpressure)werenon- significant.BMIwasnegativelycorrelatedwiththenumberofwalkingandrunningstepsandlongestnon-stopdistance. Conclusion:Thisisthefirststudyusingaccelerometrywhichshowsanassociationbetweenwalkingspeedandageinfree- living,healthyindividuals.Absolut