Economic Impact of Cystic Echinococcosis in Peru 英文参考文献.docVIP

EconomicImpactofCysticEchinococcosisinPeru PedroL.Moro1*,ChristineM.Budke2,PeterM.Schantz3,JulioVasquez4,SaulJ.Santivan?ez5 ,Jaime Villavicencio6 1DivisionofHealthcareQualityPromotion,ImmunizationSafetyOffice,CentersforDiseaseControlandPrevention,Atlanta,Georgia,UnitedStatesofAmerica,2College of Veterinary Medicine and Biomedical Sciences, Texas AM University, College Station, Texas, United States of America, 3Rollins School of Public Health, Emory University,Atlanta,Georgia,UnitedStatesofAmerica,4PortneufMedicalCenterandIdahoStateUniversity,Pocatello,Idaho,UnitedStatesofAmerica,5InstitutoPeruano deParasitologiaClinicayExperimental,Lima,Peru,6ServicioNacionaldeSanidadAgraria,MinisteriodeAgricultura,Lima,Peru Abstract Background:Cysticechinococcosis(CE)constitutesanimportantpublichealthprobleminPeru.However,nostudieshave attemptedtoestimatethemonetaryandnon-monetaryimpactofCEinPeruviansociety. Methods: We used official and published sources of epidemiological and economic information to estimate direct and indirectcostsassociatedwithlivestockproductionlossesandhumandiseaseinadditiontosurgicalCE-associateddisability adjustedlifeyears(DALYs)lost. Findings: The total estimated cost of human CE in Peru was U.S.$2,420,348 (95% CI:1,118,384–4,812,722) per year. Total estimatedlivestock-associatedcostsduetoCErangedfromU.S.$196,681(95%CI:141,641–251,629)ifonlydirectlosses(i.e., cattleandsheepliverdestruction)weretakenintoconsiderationtoU.S.$3,846,754(95%CI:2,676,181–4,911,383)ifadditional productionlosses(livercondemnation,decreasedcarcassweight,woollosses,decreasedmilkproduction)wereaccounted for.Anestimated1,139(95%CI:861–1,489)DALYswerealsolostduetosurgicalcasesofCE. Conclusions: Thispreliminary andconservative assessment of thesocio-economic impact of CE on Peru,which is based largely on official sources of information, very likely underestimates the true extent of the problem. Nevertheless, these estimatesillustratethenegativeeconomicimpactofCEinPeru. Citation:MoroPL,