Effect of Constitution on Mass of Individual Organs and Their Association with Metabolic Rate in Humans—A Detailed View on Allometric Scaling 英文参考文献.docVIP

下载本文档

1
0
约3.87万字
约 9页
2017-05-11 发布于上海
举报
版权申诉

Effect of Constitution on Mass of Individual Organs and Their Association with Metabolic Rate in Humans—A Detailed View on Allometric Scaling 英文参考文献.doc

1、本文档共9页，可阅读全部内容。
2、原创力文档（book118）网站文档一经付费（服务费），不意味着购买了该文档的版权，仅供个人/单位学习、研究之用，不得用于商业用途，未经授权，严禁复制、发行、汇编、翻译或者网络传播等，侵权必究。
3、本站所有内容均由合作方或网友上传，本站不对文档的完整性、权威性及其观点立场正确性做任何保证或承诺！文档内容仅供研究参考，付费前请自行鉴别。如您付费，意味着您自己接受本站规则且自行承担风险，本站不退款、不进行额外附加服务；查看《如何避免下载的几个坑》。如果您已付费下载过本站文档，您可以点击这里二次下载。
4、如文档侵犯商业秘密、侵犯著作权、侵犯人身权等，请点击“版权申诉”（推荐），也可以打举报电话：400-050-0827(电话支持时间：9:00-18:30)。
5、该文档为VIP文档，如果想要下载，成为VIP会员后，下载免费。
6、成为VIP后，下载本文档将扣除1次下载权益。下载后，不支持退款、换文档。如有疑问请联系我们。
7、成为VIP后，您将拥有八大权益，权益包括：VIP文档下载权益、阅读免打扰、文档格式转换、高级专利检索、专属身份标志、高级客服、多端互通、版权登记。
8、VIP文档为合作方或网友上传，每下载1次，网站将根据用户上传文档的质量评分、类型等，对文档贡献者给予高额补贴、流量扶持。如果你也想贡献VIP文档。上传文档

Effect of Constitution on Mass of Individual Organs and Their Association with Metabolic Rate in Humans—A Detailed View on Allometric Scaling 英文参考文献

EffectofConstitutiononMassofIndividualOrgansand TheirAssociationwithMetabolicRateinHumans—A DetailedViewonAllometricScaling ManfredJ.Mu¨ller1*,DirkLangemann2,IsabelGehrke1,WiebkeLater1,MartinHeller3,ClausC.Glu¨er3, StevenB.Heymsfield4,AnjaBosy-Westphal1 1Institut fu¨r Humanerna¨hrung und Lebensmittelkunde, Christian-Albrechts-Universita¨t zu Kiel, Kiel, Germany, 2Institute of Computational Mathematics, Technical UniversityBraunschweig,Braunschweig,Germany,3Klinikfu¨rDiagnostischeRadiologie,Universita¨tsklinikumSchleswigHolstein,Kiel,Germany,4PenningtonBiomedical ResearchCenter,BatonRouge,Louisiana,UnitedStatesofAmerica Abstract Restingenergyexpenditure(REE)-powerrelationshipsresultfrommultipleunderlyingfactorsincludingweightandheight. Inaddition,detailedbodycomposition,includingfatfreemass(FFM)anditscomponents,skeletalmusclemassandinternal organswithhighmetabolicrates(i.e.brain,heart,liver,kidneys),aremajordeterminantsofREE.Sincethemassofindividual organsscalestoheightaswellastoweight(and,thus,toconstitution),thevarianceintheseassociationsmayalsoaddto thevarianceinREE.Hereweaddressbodycomposition(measuredbymagneticresonanceimaging)andREE(assessedby indirectcalorimetry)inagroupof330healthyvolunteersdifferingwithrespecttoage(17–78years),sex(61%female)and BMI (15.9–47.8kg/m2). Using three dimensional data interpolation wefound that the inter-individual variance related to scalingoforganmasstoheightandweightand,thus,theconstitution-relatedvariancesineitherFFM(model1)orkidneys, muscle, brain and liver (model 2) explained up to 43% of the inter-individual variance in REE. These data are the first evidencethatconstitutionaddstothecomplexityofREE.Sinceorgansscaledifferentlyasweightaswellasheightthe‘‘fit’’ oforganmasseswithinconstitutionshouldbeconsideredasafurthertrait. Citation: Mu¨ller MJ, Langemann D, Gehrke I, Later W, Heller M, et al. (2011) Effect of Constitution on Mass of Individual Organs and Their Association with MetabolicRateinHumans—ADetailedViewonAllometricS