Friends and Symptom Dimensions in Patients with Psychosis A Pooled Analysis 英文参考文献.docVIP

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Friends and Symptom Dimensions in Patients with Psychosis A Pooled Analysis 英文参考文献.doc

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Friends and Symptom Dimensions in Patients with Psychosis A Pooled Analysis 英文参考文献

FriendsandSymptomDimensionsinPatientswith Psychosis:APooledAnalysis DomenicoGiacco1,2*,RoseMcCabe1,ThomasKallert3,4,LarsHansson5,AndreaFiorillo2,StefanPriebe1 1Unit for Social and Community Psychiatry, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom, 2Department of Psychiatry, University of Naples SUN, Naples, Italy, 3Klinik fu¨r Psychiatrie, Psychosomatik und Psychotherapie, Leipzig, Germany, 4Department of PsychiatryandPsychotherapy,DresdenUniversityofTechnology,Dresden,Germany,5DepartmentofClinicalNeuroscience,LundUniversity,Lund,Sweden Abstract Background: Having friends is associated with more favourable clinical outcomes and a higher quality of life in mental disorders. Patients with schizophrenia have fewer friends than other mentally ill patients. No large scale studies have evaluatedsofarwhatsymptomdimensionsofschizophreniaareassociatedwiththelackoffriendships. Methods:Datafromfourmulti-centrestudiesonoutpatientswithschizophreniaandrelateddisorders(ICDF20-29)were included in a pooled analysis (N=1396). We established whether patients had close friends and contact with friends by usingtheequivalentitemsonfriendshipsoftheManchesterShortAssessmentofQualityofLifeoroftheLancashireQuality of Life Profile. Symptoms were measured by the Brief Psychiatric Rating Scale or by the identical items included in the PositiveandNegativeSyndromeScale. Results: Seven hundred and sixty-nine patients (55.1%) had seen a friend in the previous week and 917 (65.7%) had someonetheyregardedasaclosefriend.Lowlevelsofnegativesymptomsandhostilityweresignificantlyassociatedwith having a close friend and contact with a friend. Overall, almost twice as many patients with absent or mild negative symptomshadmetafriendinthelastweek,comparedwiththosewithmoderatenegativesymptoms. Conclusions: Higher levels of negative symptoms and hostility are specifically associated with the lack of friendships in patientswithpsychoticdisorders