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Gene Order Phylogeny and the Evolution of Methanogens 英文参考文献
GeneOrderPhylogenyandtheEvolutionof
Methanogens
HaiweiLuo1*,ZhiyiSun2,WilliamArndt3,JianShi3,RobertFriedman1,JijunTang3
1Department of Biological Sciences, University of South Carolina, Columbia, South Carolina, United States of America, 2The Graduate Program in Organismic and
EvolutionaryBiology,UniversityofMassachusetts,Amherst,Massachusetts,UnitedStatesofAmerica,3DepartmentofComputerScienceandEngineering,Universityof
SouthCarolina,Columbia,SouthCarolina,UnitedStatesofAmerica
Abstract
MethanogensareaphylogeneticallydiversegroupbelongingtoEuryarchaeota.Previously,phylogeneticapproachesusing
largedatasetsrevealedthatmethanogenscanbegroupedintotwoclasses,‘‘ClassI’’and‘‘ClassII’’.However,somedeep
relationshipswerenotresolved.Forinstance,themonophylyof‘‘ClassI’’methanogens,whichconsistofMethanopyrales,
Methanobacteriales andMethanococcales, is disputable due toweak statistical support. In this study, we use MSOAR to
identifycommonorthologousgenesfromeightmethanogenspeciesandaThermococcalespecies(outgroup),andapply
GRAPPAandFastMEtocomputedistance-basedgeneorderphylogeny.Thegeneorderphylogenysupportstwoclassesof
methanogens, but it differs from the original classification of methanogens by placing Methanopyrales and
Methanobacteriales togetherwithMethanosarcinalesinClassIIrather thanwithMethanococcales.Thisstudysuggestsa
newclassificationschemeformethanogens.Inaddition,itindicatesthatgeneorderphylogenycancomplementtraditional
sequence-basedmethodsinaddressingtaxonomicquestionsfordeeprelationships.
Citation:LuoH,SunZ,ArndtW,ShiJ,FriedmanR,etal.(2009)GeneOrderPhylogenyandtheEvolutionofMethanogens.PLoSONE4(6):e6069.doi:10.1371/
journal.pone.0006069
Editor:IddoFriedberg,UniversityofCaliforniaSanDiego,UnitedStatesofAmerica
ReceivedMarch30,2009;AcceptedMay29,2009;PublishedJune29,2009
Copyright:?2009Luoetal.Thisisanopen-accessarticledistributedunderthetermsoftheCreativeCommonsAttributionLicense,whichpermitsunrestricted
use,distribution,andreproductioninanymedium,provi
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