Optic nerve sonography in the diagnostic evaluation of adult brain injury 英文参考文献.docVIP

Available online /content/12/3/R67 Research Open Access Vol 12 No 3 Optic nerve sonography in the diagnostic evaluation of adult brain injury Theodoros Soldatos1, Dimitrios Karakitsos2, Katerina Chatzimichail1, Matilda Papathanasiou1, Athanasios Gouliamos1 and Andreas Karabinis2 1Second Department of Radiology, Attikon University Hospital, 1 Rimin st, 124 62, Athens, Greece 2Department of Intensive Care, General State Hospital of Athens, 154 Mesogeion ave, 115 27, Athens, Greece Corresponding author: Andreas Karabinis, akarabinis@ath.forthnet.gr Received: 20 Feb 2008 Revisions requested: 2 Apr 2008 Revisions received: 16 Apr 2008 Accepted: 13 May 2008 Published: 13 May 2008 Critical Care 2008, 12:R67 (doi:10.1186/cc6897) This article is online at: /content/12/3/R67 ? 2008 Soldatos et al.; licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Introduction The optic nerve sheath diameter (ONSD) may be Results ONSD and estimated ICP were both significantly increased (6.1 ± 0.7 mm and 26.2 ± 8.7 mmHg, respectively; P 0.0001) in patients with severe brain injury as compared with patients with moderate brain injury (4.2 ± 1.2 mm and 12.0 ± 3.6 mmHg) and compared with control individuals (3.6 ± 0.6 mm and 10.3 ± 3.1 mmHg). Furthermore, in patients with severe brain injury the ONSD measurements were strongly correlated with estimated ICP values (r = 0.80, P 0.0001) as well as with the neuroimaging scale results (r = 0.82, P 0.001). In the increased in brain-injured patients, especially children, with whether intracranial measurements hypertension. We correlated investigated simultaneous noninvasive and invasive measurements of the intracranial pressure (ICP) in brain-injured adults. of ONSD