Out-of-hospital CPR better outcome for our patients 英文参考文献.docVIP

Golia et al. Critical Care 2011,15:149 /content/15/2/149 COMMENTA RY Out-of-hospital CPR: better outcome for our patients Enrica Golia , Maddalena Piro and Marco Tubaro * 1,2 2 2 See related research by Gr?sner et al., /content/15/1/R61 OHCA is a leading cause of death in developed countries and early resuscitation attempts through basic and then advanced cardiac life support therapies are crucial to improve survival rates and neurological out- Abstract Out-of-hospital cardiac arrest is a leading cause of death in developed countries and early resuscitation attempts are crucial to improve survival rates and neurological outcome. Gr?sner and colleagues c e outcome of patients experiencing OHCA remains poor and varies signi? cantly, according to rhythm characteristics (shockable vs. nonshockable) and other clinical features. However, the long-term prognosis of patients discharged alive has improved [3]. Because approxi mately 70% of OHCA patients have underlying acute myocardial infarction, several studies focused on the role of reperfusion strategies, such as thrombolysis and primary PCI, during cardiac arrest or, most often, after return of spontaneous circulation [4-7]. In parti cu- lar, immediate successful PCI is associated with improved hospital survival, in the absence of obvious extracardiac causes for the arrest [4-6]. Primary PCI is e? ective independently of the electrocardiogram pattern (that is, with or without ST-segment elevation) [4], suggesting a poor predictive value of the electrocardiogram in identi- fying patients who may bene? t from coronary inter vention. Since techniques in resuscitation have improved, the popu lation of patients with anoxic brain injury is grow- performed an intriguing analysis on the combined approach