Oxidative stress in term small for gestational age neonates born to undernourished mothers a case control study 英文参考文献.docVIP
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Oxidative stress in term small for gestational age neonates born to undernourished mothers a case control study 英文参考文献
BMC Pediatrics
BioMedCentral
Research article
Open Access
Oxidative stress in term small for gestational age neonates born to
undernourished mothers: a case control study
Piyush Gupta*1, Manish Narang1, BD Banerjee2 and Srikanta Basu3
Address: 1Department of Pediatrics, University College of Medical Sciences and Guru Tegh Bahadur Hospital, New Delhi 110 095, India,
2Department of Biochemistry, University College of Medical Sciences, New Delhi 110 095, India and 3Department of Pediatrics, Government
Medical College, Sector 32, Chandigarh, India
Email: Piyush Gupta* - drpiyush@.in; Manish Narang - manishnarang_2710@; BD Banerjee - banerjeebd@;
Srikanta Basu - srikantabasu@
* Corresponding author
Published: 20 July 2004
Received: 12 February 2004
Accepted: 20 July 2004
BMC Pediatrics 2004, 4:14
doi:10.1186/1471-2431-4-14
This article is available from: /1471-2431/4/14
? 2004 Gupta et al; licensee BioMed Central Ltd. This is an Open Access article: verbatim copying and redistribution of this article are permitted in all
media for any purpose, provided this notice is preserved along with the articles original URL.
Abstract
Background: The objective of this study was to assess the status of oxidative stress in term small
for gestational age (SGA) newborn infants born to undernourished mothers by estimating levels of
erythrocyte
superoxide
dismutase
(SOD),
catalase,
reduced
glutathione,
and
serum
malondialdehyde (MDA) in cord blood and comparing them to healthy appropriate for gestational
age (AGA) controls. This was done in a case control design at a tertiary level teaching hospital.
Methods: We included 20 singleton healthy SGA newborn infants born between 38–40 weeks to
undernourished mothers with a) post-pregnancy weight 50 kg or height 145 cm AND b)
hemoglobin 8.0 g/dL or serum albumin 2.5 g/dL. An equal number of age and sex matched AGA
newborn infants born to healthy mothers served as Controls. Mothers with other risk factors
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