PopMod a longitudinal population model with two interacting disease states 英文参考文献.docVIP

Cost Effectiveness and Resource Allocation BioMedCentral Methodology Open Access PopMod: a longitudinal population model with two interacting disease states Jeremy A Lauer*1, Klaus R?hrich2, Harald Wirth2, Claude Charette3, Steve Gribble3 and Christopher JL Murray1 Address: 1Global Programme on Evidence for Health Policy (GPE/EQC), World Health Organization, 1211 Geneva 27, SWITZERLAND, 2Creative Services, Technoparc Pays de Gex, 55 rue Auguste Piccard, 01630 St Genis Pouilly, FRANCE and 3Statistics Canada, R.H Coats Building, Holland Avenue, Ottawa, Ontario K1A 0T6, CANADA Email: Jeremy A Lauer* - lauerj@; Klaus R?hrich - Klaus.Roehrich@creative-services.fr; Harald Wirth - Harold.Wirth@creative-services.fr; Claude Charette - Claude.Charette@statcan.ca; Steve Gribble - Steve.Gribble@statcan.ca; Christopher JL Murray - murrayc@ * Corresponding author Published: 26 February 2003 Received: 25 February 2003 Accepted: 26 February 2003 Cost Effectiveness and Resource Allocation 2003, 1:6 This article is available from: /content/1/1/6 ? 2003 Lauer et al; licensee BioMed Central Ltd. This is an Open Access article: verbatim copying and redistribution of this article are permitted in all media for any purpose, provided this notice is preserved along with the articles original URL. Abstract This article provides a description of the population model PopMod, which is designed to simulate the health and mortality experience of an arbitrary population subjected to two interacting disease conditions as well as all other background causes of death and disability. Among population models with a longitudinal dimension, PopMod is unique in modelling two interacting disease conditions; among the life-table family of population models, PopMod is unique in not assuming statistical independence of the diseases of interest, as well as in modelling age and time independently. Like other multi-state models, however, PopMod tak