Positive Association Between Hepatitis C Infection and Oral Cavity Cancer A Nationwide Population-Based Cohort Study in Taiwan 英文参考文献.docVIP
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Positive Association Between Hepatitis C Infection and Oral Cavity Cancer A Nationwide Population-Based Cohort Study in Taiwan 英文参考文献
PositiveAssociationBetweenHepatitisCInfectionand
OralCavityCancer:ANationwidePopulation-Based
CohortStudyinTaiwan
Fu-HsiungSu1,2,Shih-NiChang3,4,5,Pei-ChunChen5,6,Fung-ChangSung5,7,Shiang-FuHuang8 ,Hung-
YiChiou1,9,Chien-TienSu1,2,Cheng-ChiehLin10,11,12,Chih-ChingYeh1,7
*
1SchoolofPublicHealth,CollegeofPublicHealthandNutrition,TaipeiMedicalUniversity,Taipei,Taiwan,2DepartmentofFamilyMedicine,TaipeiMedicalUniversity
Hospital, Taipei, Taiwan, 3The Ph.D. Program for Cancer Biology and Drug Discovery, China Medical University, Taichung, Taiwan, 4Institute of Biomedical Sciences,
AcademiaSinica,Taipei,Taiwan,5ManagementOfficeforHealthData,ChinaMedicalUniversityHospital,Taichung,Taiwan,6GraduateInstituteofEpidemiologyand
Preventive Medicine, National Taiwan University College of Public Health, Taipei, Taiwan, 7Department of Public Health, China Medical University, Taichung, Taiwan,
8DepartmentofOtolaryngology,HeadandNeckSurgery,ChangGungMemorialHospital,ChangGungUniversity,Tao-Yuan,Taiwan,9CenterofExcellenceforCancer
Research, Taipei Medical University, Taipei, Taiwan, 10Department of Family Medicine, China Medical University Hospital, Taichung, Taiwan, 11School of Medicine,
College of Medicine, China Medical University, Taichung, Taiwan, 12Department of Healthcare Administration, College of Health Science, Asia University, Taichung,
Taiwan
Abstract
Objectives: The association between viral hepatitis (B and C) and oral cavity cancer has been widely debated. This
nationwide,population-basedcohortstudyassessedthesubsequentriskoforalcavitycanceramongpatientswithchronic
viralhepatitisinfection.
MaterialsandMethods:Datawereretrievedfrominsuranceclaimsdataof1,000,000randomlysampledindividualscovered
under the Taiwan National Health Insurance system. We identified a total of 21,199 adults with chronic viral hepatitis
infection (12,369 with HBV alone, 5,311 with HCV alone, and 3,519 with HBV/HCV dual infections) from 2000–2005.
Comparisongroupcomprised84,796sex-andage-matchedsu
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