Predicting Decisions in Human Social Interactions Using Real-Time fMRI and Pattern Classification 英文参考文献.docVIP
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Predicting Decisions in Human Social Interactions Using Real-Time fMRI and Pattern Classification 英文参考文献
PredictingDecisionsinHumanSocialInteractionsUsing
Real-TimefMRIandPatternClassification
MauriceHollmann1,3*.,JochemW.Rieger2.,SebastianBaecke1,RalfLu¨tzkendorf1,CharlesMu¨ller1,
DanielaAdolf1,JohannesBernarding1
1Medical Faculty, Institute for Biometry and Medical Computer Science, University Magdeburg, Magdeburg, Germany, 2Department of Neurology, Medical Faculty,
UniversityMagdeburg,Magdeburg,Germany,3DepartmentofNeurology,MaxPlanckInstituteforHumanCognitiveandBrainSciences,Leipzig,Germany
Abstract
Negotiationandtradetypicallyrequireamutualinteractionwhilesimultaneouslyrestinginuncertaintywhichdecisionthe
partnerultimatelywillmakeattheendoftheprocess.Assessingalreadyduringthenegotiationinwhichdirectionone’s
counterparttendswouldprovideatremendousadvantage.Recently,neuroimagingtechniquescombinedwithmultivariate
patternclassificationoftheacquireddatahavemadeitpossibletodiscriminatesubjectivestatesofmindonthebasisof
their neuronal activation signature. However, to enable an online-assessment of the participant’s mind state both
approachesneedtobeextendedtoareal-timetechnique.Bycombiningreal-timefunctionalmagneticresonanceimaging
(fMRI) and online pattern classification techniques, we show that it is possible to predict human behavior during social
interactionbeforetheinteractingpartnercommunicatesaspecificdecision.Averageaccuracyreachedapproximately70%
whenwepredictedonlinethedecisionsofvolunteersplayingtheultimatumgame,awell-knownparadigmineconomic
gametheory.Ourresultsdemonstratethesuccessfulonlineanalysisofcomplexemotionalandcognitivestatesusingreal-
timefMRI,whichwillenableamajorbreakthroughforsocialfMRIbyprovidinginformationaboutmentalstatesofpartners
alreadyduringthemutualinteraction.Interestingly,anadditionalwholebrainclassificationacrosssubjectsconfirmedthe
onlineresults:anteriorinsula,ventralstriatum,andlateralorbitofrontalcortex,knowntoactinemotionalself-regulationand
rewardprocessingforadjustmentofbehavior,appearedtobestrongdeterminantsoflaterovertbehavi
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