Predicting post-trauma stress symptoms from pre-trauma psychophysiologic reactivity, personality traits and measures of psychopathology 英文参考文献.docVIP
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Predicting post-trauma stress symptoms from pre-trauma psychophysiologic reactivity, personality traits and measures of psychopathology 英文参考文献
Orretal.BiologyofMoodAnxietyDisorders2012,2:8
/content/2/1/8
Biology of
Mood Anxiety Disorders
RESEARCH
OpenAccess
Predictingpost-traumastresssymptomsfrom
pre-traumapsychophysiologicreactivity,
personalitytraitsandmeasures
ofpsychopathology
ScottPOrr1,2*,NatashaBLasko1,2,MichaelLMacklin1,2,SuzanneLPineles3,4,YuchiaoChang5andRogerKPitman1
Abstract
Background:Mostindividualsexposedtoatraumaticeventdonotdeveloppost-traumaticstressdisorder(PTSD),
althoughmanyindividualsmayexperiencesub-clinicallevelsofpost-traumaticstresssymptoms(PTSS).Thereare
notableindividualdifferencesinthepresenceandseverityofPTSSamongindividualswhoreportseemingly
comparabletraumaticevents.IndividualdifferencesinPTSSfollowingexposuretotraumaticeventscouldbe
influencedbypre-traumavulnerabilitiesfordevelopingPTSS/PTSD.
Methods:Pre-traumapsychological,psychophysiologicalandpersonalityvariableswereprospectivelyassessedfor
theirpredictiverelationshipswithpost-traumaticstresssymptoms(PTSS).Policeandfirefightertraineesweretested
atthestartoftheirprofessionaltraining(i.e.,pre-trauma;n=211)andagainseveralmonthsafterexposuretoa
potentiallytraumaticevent(i.e.,post-trauma,n=99).Pre-traumaassessmentsincludeddiagnosticinterviews,
psychologicalandpersonalitymeasuresandtwopsychophysiologicalassessmentprocedures.The
psychophysiologicalassessmentsmeasuredpsychophysiologicreactivitytoloudtonesandtheacquisitionand
extinctionofaconditionedfearresponse.Post-traumaassessmentincludedameasureofpsychophysiologic
reactivityduringrecollectionofthetraumaticeventusingascript-drivenimagerytask.
Results:LogisticstepwiseregressionidentifiedthecombinationoflowerIQ,higherdepressionscoreandpoorer
extinctionofforehead(corrugator)electromyogramresponsesaspre-traumapredictorsofhigherPTSS.The
combinationoflowerIQandincreasedskinconductance(SC)reactivitytoloudtoneswereidentifiedaspre-trauma
predictorsofhigherpost-traumapsychophysiologicreactivityduringrecollectionofthetraumaticevent.A
univariaterelationshipwasalsoobservedbetweenpre-tr
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