Preeclampsia complicated by advanced maternal age a registry-based study on primiparous women in Finland 1997–2008 英文参考文献.docVIP

下载本文档

10
0
约2.25万字
约 5页
2017-05-12 发布于上海
举报
版权申诉

Preeclampsia complicated by advanced maternal age a registry-based study on primiparous women in Finland 1997–2008 英文参考文献.doc

1、本文档共5页，可阅读全部内容。
2、原创力文档（book118）网站文档一经付费（服务费），不意味着购买了该文档的版权，仅供个人/单位学习、研究之用，不得用于商业用途，未经授权，严禁复制、发行、汇编、翻译或者网络传播等，侵权必究。
3、本站所有内容均由合作方或网友上传，本站不对文档的完整性、权威性及其观点立场正确性做任何保证或承诺！文档内容仅供研究参考，付费前请自行鉴别。如您付费，意味着您自己接受本站规则且自行承担风险，本站不退款、不进行额外附加服务；查看《如何避免下载的几个坑》。如果您已付费下载过本站文档，您可以点击这里二次下载。
4、如文档侵犯商业秘密、侵犯著作权、侵犯人身权等，请点击“版权申诉”（推荐），也可以打举报电话：400-050-0827(电话支持时间：9:00-18:30)。
5、该文档为VIP文档，如果想要下载，成为VIP会员后，下载免费。
6、成为VIP后，下载本文档将扣除1次下载权益。下载后，不支持退款、换文档。如有疑问请联系我们。
7、成为VIP后，您将拥有八大权益，权益包括：VIP文档下载权益、阅读免打扰、文档格式转换、高级专利检索、专属身份标志、高级客服、多端互通、版权登记。
8、VIP文档为合作方或网友上传，每下载1次，网站将根据用户上传文档的质量评分、类型等，对文档贡献者给予高额补贴、流量扶持。如果你也想贡献VIP文档。上传文档

Preeclampsia complicated by advanced maternal age a registry-based study on primiparous women in Finland 1997–2008 英文参考文献

Lamminp??etal.BMCPregnancyandChildbirth2012,12:47 /1471-2393/12/47 RESEARCH ARTICLE OpenAccess Preeclampsiacomplicatedbyadvancedmaternal age:aregistry-basedstudyonprimiparous womeninFinland1997–2008 ReetaLamminp??1*,KatriVehvil?inen-Julkunen2,MikaGissler3,4andSeppoHeinonen5 Abstract Background:Preeclampsiaisafrequentsyndromeanditscausehasbeenlinkedtomultiplefactors,making preventionofthesyndromeacontinuouschallenge.Oneofthesuggestedriskfactorsforpreeclampsiaisadvanced maternalage.IntheWesterncountries,maternalageatfirstdeliveryhasbeensteadilyincreasing,yetfewstudies haveexaminedwomenofadvancedmaternalagewithpreeclampsia.Thepurposeofthisregistry-basedstudywas tocomparetheobstetricoutcomesinprimiparousandpreeclampticwomenyoungerandolderthan35years. Methods:Theregistry-basedstudyuseddatafromthreeFinnishhealthregistries:FinnishMedicalBirthRegister, FinnishHospitalDischargeRegisterandRegisterofCongenitalMalformations.Thesamplecontainedwomenunder 35yearsofage(N=15,437)comparedwiththose35andover(N=2,387)whowerediagnosedwithpreeclampsia andhadtheirfirstsingletonbirthinFinlandbetween1997and2008.Inmultivariatemodeling,themainoutcome measureswerePretermdelivery(before34and37weeks),lowApgarscore(5min.),small-for-gestational-age,fetal death,asphyxia,Cesareandelivery,induction,bloodtransfusionandadmissiontoaNeonatalIntensiveCareUnit. Results:Womenofadvancedmaternalage(AMA)exhibitedmorepreeclampsia(9.4%)thanyoungerwomen (6.4%).Theyhadmorepriorterminations(0.001),weremorelikelytohaveabodymassindex(BMI)25(0.001), hadmoreinvitrofertilization(IVF)(0.001)andotherfertilitytreatments(0.001)andahigherincidenceof maternaldiabetes(0.001)andchronichypertension(0.001).Multivariatelogisticregressionindicatedthatwomen ofAMAhadhigherratesof:pretermdeliverybefore37weeks19.2%(OR1.39CI1.24to1.56)andbefore34weeks 8.7%(OR1.68CI1.43to2.00)lowApgarscoresat5min.7.1%(OR1.37CI1.00to1.88),Small-for-GestationalAge (SGA)26.5%(OR1.42CI1.28to1.57),Asphyxia12.1%(OR1.54CI1.34to1.77),Caesareandelivery50%(OR2.0