Preparation of an Eight-Membered Sesquiterpene Lactone Resulting from Sequential Gif System GoAggIII and MCPBA Oxidation of ( )-10β,14-Dihydroxy-allo-aromadendrane 英文参考文献.docVIP

下载本文档

1
0
约1.16万字
约 5页
2017-05-12 发布于上海
举报
版权申诉

Preparation of an Eight-Membered Sesquiterpene Lactone Resulting from Sequential Gif System GoAggIII and MCPBA Oxidation of ( )-10β,14-Dihydroxy-allo-aromadendrane 英文参考文献.doc

1、本文档共5页，可阅读全部内容。
2、原创力文档（book118）网站文档一经付费（服务费），不意味着购买了该文档的版权，仅供个人/单位学习、研究之用，不得用于商业用途，未经授权，严禁复制、发行、汇编、翻译或者网络传播等，侵权必究。
3、本站所有内容均由合作方或网友上传，本站不对文档的完整性、权威性及其观点立场正确性做任何保证或承诺！文档内容仅供研究参考，付费前请自行鉴别。如您付费，意味着您自己接受本站规则且自行承担风险，本站不退款、不进行额外附加服务；查看《如何避免下载的几个坑》。如果您已付费下载过本站文档，您可以点击这里二次下载。
4、如文档侵犯商业秘密、侵犯著作权、侵犯人身权等，请点击“版权申诉”（推荐），也可以打举报电话：400-050-0827(电话支持时间：9:00-18:30)。
5、该文档为VIP文档，如果想要下载，成为VIP会员后，下载免费。
6、成为VIP后，下载本文档将扣除1次下载权益。下载后，不支持退款、换文档。如有疑问请联系我们。
7、成为VIP后，您将拥有八大权益，权益包括：VIP文档下载权益、阅读免打扰、文档格式转换、高级专利检索、专属身份标志、高级客服、多端互通、版权登记。
8、VIP文档为合作方或网友上传，每下载1次，网站将根据用户上传文档的质量评分、类型等，对文档贡献者给予高额补贴、流量扶持。如果你也想贡献VIP文档。上传文档

Preparation of an Eight-Membered Sesquiterpene Lactone Resulting from Sequential Gif System GoAggIII and MCPBA Oxidation of ( )-10β,14-Dihydroxy-allo-aromadendrane 英文参考文献

Molecules 2005, 10, 1010-1014 molecules ISSN 1420-3049 Preparation of an Eight-Membered Sesquiterpene Lactone Resulting from Sequential Gif System GoAggIII and MCPBA Oxidation of (+)-10β,14-Dihydroxy-allo-aromadendrane Márcia M. L. de Bodas 1, Maria Rita Marques 2, Adilson Beatriz 1 and Dênis P. de Lima 1,* 1 Universidade Federal de Mato Grosso do Sul, Departamento de Química / CCET – CP 549 - 79070- 900 – Campo Grande (MS) – Brazil. Tel. +55 (67)-345-3578, Fax +55 (67) 345-3552 2 Universidade Federal de Mato Grosso do Sul, Departamento de Morfofisiologia / CCBS – CP 549 - 79070-900 – Campo Grande (MS) - Brazil * Author to whom correspondence should be addressed; E-mail: dlima@nin.ufms.br Received: 8 December 2004 / Accepted: 2 March 2005 / Published: 31 August 2005 Abstract: Studies aimed at a comparison of chemical, biomimetic (Gif system GoAggIII) and enzymatic (CHMO) transformations of natural (+)-10β,14-dihydroxy-allo- aromadendrane have led to preparation of an eight-member sesquiterpene lactone. Keywords: (+)-10β,14-dihydroxy-allo-aromadendrane, (-)-allo-aromandendrone, apo- aromadendrone, eight-member sesquiterpene lactone, GoAggIII, CHMO, MCPBA, Baeyer-Villiger Introduction Our research group has been undertaking an effort to perform random transformations in natural compounds with the purpose of obtaining novel, potentially bioactive derivatives. The sesquiterpene (+)-10β,14-dihydroxy-allo-aromadendrane (1) (Figure 1), has already been target of different studies reported by our group. Compound 1 is a natural product isolated from Pulicaria paludosa [1] and Duguetia glabriuscula [2]. Investigations concerning chemical modification [3], microbial transformation [4], electrolysis [5] and NMR assignments [6] of this molecule have demonstrated a great reaction versatility leading to unique carbon frameworks. Molecules 2005, 10 1011 Figure 1: (+)-10β,