Prevalence of asthma in Portugal - The Portuguese National Asthma Survey 英文参考文献.docVIP

Prevalence of asthma in Portugal - The Portuguese National Asthma Survey 英文参考文献.doc

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Prevalence of asthma in Portugal - The Portuguese National Asthma Survey 英文参考文献

Sa-Sousaetal.ClinicalandTranslationalAllergy2012,2:15 /content/2/1/15 RESEARCH OpenAccess PrevalenceofasthmainPortugal-The PortugueseNationalAsthmaSurvey AnaSa-Sousa1,MárioMorais-Almeida2,3,LuisFilipeAzevedo1,4,RosaCarvalho5,TiagoJacinto1,4,6,AnaTodo-Bom3,7, CarlosLoureiro3,7,AntónioBugalho-Almeida8,9,JeanBousquet10andJo?oAlmeidaFonseca1,4,6,11* Abstract Background:Asthmaisafrequentchronicrespiratorydiseaseinbothchildrenandadults.However,fewdataon asthmaprevalenceareavailableinPortugal.ThePortugueseNationalAsthmaSurveyisthefirstnationwidestudy thatusesstandardizedmethods.WeaimedtoestimatetheprevalenceofcurrentasthmainthePortuguese populationandtoassesstheassociationbetween‘Currentasthma’andcomorbiditiessuchasupperairways disease. Methods:Across-sectional,population-based,telephoneinterviewsurveyincludingallmunicipalitiesofPortugal wasundertaken.ParticipantswererandomlyselectedtoansweraquestionnairebasedonthePortugueseversion oftheGA2LENsurvey.‘Currentasthma’wasdefinedasself-reportedlifetimeasthmaandatleastoneof3 symptomsinthelast12months:wheezing,wakingwithbreathlessnessorhavinganasthmaattack. Results:Datawereobtainedfor6003respondents,withmeanageof38.9(95%CI38.2-39.6)yearsand57.3% females.InthePortuguesepopulation,theprevalenceof‘Currentasthma’was6.8%(95%CI6.0-7.7)andof‘Lifetime asthma’was10.5%(95%CI9.5-11.6)UsingGA2LENdefinitionforasthma,ourprevalenceestimatewas7.8%(95%CI 7.0-8.8).Rhinitishadastrongassociationwithasthma(AdjustedOR3.87,95%CI2.90-5.18)andtheassociation betweenupperairwaydiseasesandasthmawasstrongerinpatientswithbothrhinitisandsinusitis(AdjustedOR 13.93,95%CI6.60-29.44). Conclusions:Currentasthmaaffects695000Portuguese,withaprevalenceof6.8%.Peoplewhoreportedboth rhinitisandsinusitishadthehighestriskofhavingasthma. Keywords:Asthma,Computer-assisted-telephone–interviewing(CATI),Epidemiology,Prevalence Background symptoms prevalence is limited for ages between 20– Asthma isa chronic inflammatory disease of the airways 44yearsoldin EuropeanCommunityRe

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