Rescue treatment with terlipressin in children with refractory septic shock a clinical study 英文参考文献.docVIP

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Rescue treatment with terlipressin in children with refractory septic shock a clinical study 英文参考文献.doc

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Rescue treatment with terlipressin in children with refractory septic shock a clinical study 英文参考文献

Available online /content/10/1/R20 Research Open Access Vol 10 No 1 Rescue treatment with terlipressin in children with refractory septic shock: a clinical study Antonio Rodríguez-Nú?ez1, Jesús López-Herce2, Javier Gil-Antón3, Arturo Hernández4, Corsino Rey5 and the RETSPED Working Group of the Spanish Society of Pediatric Intensive Care 1Clinical Assistant, Pediatric Emergency and Critical Care Division, Department of Pediatrics, Hospital Clínico Universitario de Santiago de Compostela, Servicio Galego de Saude (SERGAS) and University of Santiago de Compostela, Santiago de Compostela, Spain 2Clinical Assistant, Pediatric Intensive Care Unit, Hospital General Universitario Gregorio Mara?ón, Madrid, Spain 3Clinical Assistant, Pediatric Intensive Care Unit, Hospital de Cruces, Barakaldo, Spain 4Clinical Assistant, Pediatric Intensive Care Unit, Hospital Puerta del Mar, Cádiz, Spain 5Director, Pediatric Intensive Care Unit, Hospital Universitario Central de Asturias, Oviedo, Spain Corresponding author: Antonio Rodríguez-Nú?ez, Antonio.Rodriguez.Nunez@sergas.es Received: 13 Oct 2005 Revisions requested: 6 Dec 2005 Revisions received: 18 Dec 2005 Accepted: 9 Jan 2006 Published: 31 Jan 2006 Critical Care 2006, 10:R20 (doi:10.1186/cc3984) This article is online at: /content/10/1/R20 ? 2006 Rodríguez-Nú?ez et al.; licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Introduction Refractory septic shock has dismal prognosis despite aggressive therapy. The purpose of the present study is to report the effects of terlipressin (TP) as a rescue treatment in children with catecholamine refractory hypotensive septic shock. one hour in 14 out of 16 patients. The mean (range) arterial blood pressure 30 minutes after TP a