Scar-like lesion on dorsal nose (cellular neurothekeoma) 英文参考文献.docVIP

Head Face Medicine BioMedCentral Case report Open Access Scar-like lesion on dorsal nose (cellular neurothekeoma) Larissa Dorina López-Cepeda*1, Gisela Navarrete-Franco2, Josefa Novales- Santacoloma3 and Julio Enriquez-Merino4 Address: 1Consultation, Centro Dermatológico Dr. Ladislao de la Pascua, Mexico city, Mexico, 2Dermatopathology Department, Centro Dermatológico Dr. Ladislao de la Pascua, Mexico city, Mexico, 3Dermatopathology Department, Centro Dermatológico Dr. Ladislao de la Pascua, Mexico city, Mexico and 4Surgery Department, Centro Dermatológico Dr. Ladislao de la Pascua, Mexico city, Mexico Email: Larissa Dorina López-Cepeda* - larisslo@.mx; Gisela Navarrete-Franco - not@; Josefa Novales- Santacoloma - not@; Julio Enriquez-Merino - enriquezdermaqx@ * Corresponding author Published: 30 November 2007 Received: 13 February 2006 Accepted: 30 November 2007 Head Face Medicine 2007, 3:39 doi:10.1186/1746-160X-3-39 This article is available from: /content/3/1/39 ? 2007 López-Cepeda et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Neurothekeomas are tumors of neural differentiation and of unknown origin that occur in females at the 2nd and 3rd decades of life. They usually affect the face with an unspecific clinical aspect. The histological features include cellular or mixoid differentiation and immunohistochemistry can be positive for protein s-100, vimentin and epithelilal membrane antigen (EMA). This case report presents a 13-year-old female patient with nasal neurothekeoma of cellular variety and strongly positive for vimentin and s-100; and negative for EMA. Background NK presents frequently in females between 10–66 years (especially among the 2nd and 3rd decades of life). It is