Sgt1, but not Rar1, is essential for the RB-mediated broad-spectrum resistance to potato late blight 英文参考文献.docVIP

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Sgt1, but not Rar1, is essential for the RB-mediated broad-spectrum resistance to potato late blight 英文参考文献.doc

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Sgt1, but not Rar1, is essential for the RB-mediated broad-spectrum resistance to potato late blight 英文参考文献

BMC Plant Biology BioMedCentral Research article Open Access Sgt1, but not Rar1, is essential for the RB-mediated broad-spectrum resistance to potato late blight Pudota B Bhaskar1, John A Raasch2, Lara C Kramer1, Pavel Neumann1, Susan M Wielgus1, Sandra Austin-Phillips2 and Jiming Jiang*1 Address: 1Department of Horticulture, University of Wisconsin-Madison, Madison, WI 53706, USA and 2Biotechnology Center, University of Wisconsin-Madison, Madison, WI 53706, USA Email: Pudota B Bhaskar - pudota1@; John A Raasch - jaraasch@; Lara C Kramer - lmcolton@; Pavel Neumann - neumann@umbr.cas.cz; Susan M Wielgus - swielgus@; Sandra Austin-Phillips - sandra@; Jiming Jiang* - jjiang1@ * Corresponding author Published: 23 January 2008 Received: 13 October 2007 Accepted: 23 January 2008 BMC Plant Biology 2008, 8:8 doi:10.1186/1471-2229-8-8 This article is available from: /1471-2229/8/8 ? 2008 Bhaskar et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Background: Late blight is the most serious potato disease world-wide. The most effective and environmentally sound way for controlling late blight is to incorporate natural resistance into potato cultivars. Several late blight resistance genes have been cloned recently. However, there is almost no information available about the resistance pathways mediated by any of those genes. Results: We previously cloned a late blight resistance gene, RB, from a diploid wild potato species Solanum bulbocastanum. Transgenic potato lines containing a single RB gene showed a rate-limiting resistance against all known races of Phytophthora infestans, the late blight pathogen. To better understand the RB-mediated resistance we silenced the potato Rar1 and Sgt1 ge