Stimulation of Apolipoprotein A-IV expression in Caco-2TC7 enterocytes and reduction of triglyceride formation in 3T3-L1 adipocytes by potential anti-obesity Chinese herbal medicines 英文参考文献.docVIP
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Stimulation of Apolipoprotein A-IV expression in Caco-2TC7 enterocytes and reduction of triglyceride formation in 3T3-L1 adipocytes by potential anti-obesity Chinese herbal medicines 英文参考文献
Chinese Medicine
BioMedCentral
Research
Open Access
Stimulation of Apolipoprotein A-IV expression in Caco-2/TC7
enterocytes and reduction of triglyceride formation in 3T3-L1
adipocytes by potential anti-obesity Chinese herbal medicines
Ava Jiangyang Guo1, Roy Chi-yan Choi1, Anna Wing-han Cheung1, Jun Li1,
Ivy Xiaoying Chen1, Tina Tingxia Dong1, Karl Wah-keung Tsim1 and
Brad Wing-chuen Lau*2
Address: 1Department of Biology and the Center for Chinese Medicine, Hong Kong University of Science and Technology, Clear Water Bay Road,
Hong Kong SAR, PR China and 2Macao Institute for Applied Research in Medicine and Health (MUST Foundation), Avenida Wai Long, Taipa,
Macao SAR, PR China
Email: Ava Jiangyang Guo - avaguo@ust.hk; Roy Chi-yan Choi - roychoi@ust.hk; Anna Wing-han Cheung - boanna@ust.hk;
Jun Li - lijun@ust.hk; Ivy Xiaoying Chen - biovy@ust.hk; Tina Tingxia Dong - botina@ust.hk; Karl Wah-keung Tsim - botsim@ust.hk;
Brad Wing-chuen Lau* - wclau@.mo
* Corresponding author
Published: 26 March 2009
Received: 3 September 2008
Accepted: 26 March 2009
Chinese Medicine 2009, 4:5
doi:10.1186/1749-8546-4-5
This article is available from: /content/4/1/5
? 2009 Guo et al; licensee BioMed Central Ltd.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0),
which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Background: Chinese medicine has been proposed as a novel strategy for the prevention of
metabolic disorders such as obesity. The present study tested 17 Chinese medicinal herbs were
tested for their potential anti-obesity effects.
Methods: The herbs were evaluated in terms of their abilities to stimulate the transcription of
Apolipoprotein A-IV (ApoA-IV) in cultured Caco-2/TC7 enterocytes. The herbs that showed
stimulating effects on ApoA-IV transcription were further evaluate
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