Synthesis of Dihydrouracils Spiro-Fused to Pyrrolidines Druglike Molecules Based on the 2-Arylethyl Amine Scaffold 英文参考文献.docVIP

Molecules 2010, 15, 2269-2301; doi:10.3390/moleculeOPEN ACCESS molecules ISSN 1420-3049 /journal/molecules Article Synthesis of Dihydrouracils Spiro-Fused to Pyrrolidines: Druglike Molecules Based on the 2-Arylethyl Amine Scaffold Daniel Blanco-Ania 1, Carolina Valderas-Cortina 1, Pedro H.H. Hermkens 2, Leo A.J.M. Sliedregt 3, Hans W. Scheeren 1and Floris P.J.T. Rutjes 1,* 1 Institute for Molecules and Materials, Radboud University Nijmegen, Heyendaalseweg 135, 6525 AJ Nijmegen, The Netherlands 2 MSD Research Laboratories, P.O. Box 20, 5340 BH Oss, The Netherlands 3 Solvay Ph