The anti-CD74 humanized monoclonal antibody, milatuzumab, which targets the invariant chain of MHC II complexes, alters B-cell proliferation, migration, and adhesion molecule expression 英文参考文献.docVIP
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The anti-CD74 humanized monoclonal antibody, milatuzumab, which targets the invariant chain of MHC II complexes, alters B-cell proliferation, migration, and adhesion molecule expression 英文参考文献
Fr?lichetal.ArthritisResearchTherapy2012,14:R54
/content/14/2/R54
RESEARCH ARTICLE
OpenAccess
Theanti-CD74humanizedmonoclonalantibody,
milatuzumab,whichtargetstheinvariantchain
ofMHCIIcomplexes,altersB-cellproliferation,
migration,andadhesionmoleculeexpression
DanielaFr?lich1,2?,DanielaBlaβfeld1,2?,KarinReiter1,2,ClaudiaGiesecke1,2,CapucineDaridon1,2,HenrikEMei1,2,
GerdRBurmester1,2,DavidMGoldenberg3,AbdulagabarSalama4andThomasD?rner1,2*
Abstract
Introduction:TargetingCD74astheinvariantchainofmajorhistocompatibilitycomplexes(MHC)becamepossible
bytheavailabilityofaspecifichumanizedmonoclonal
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