The balance of expression of PTPN22 splice forms is significantly different in rheumatoid arthritis patients compared with controls 英文参考文献.docVIP
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The balance of expression of PTPN22 splice forms is significantly different in rheumatoid arthritis patients compared with controls 英文参考文献
Ronningeretal.GenomeMedicine2012,4:2
/content/4/1/2
RESEARCH
OpenAccess
ThebalanceofexpressionofPTPN22spliceforms
issignificantlydifferentinrheumatoidarthritis
patientscomparedwithcontrols
MarcusRonninger1*?,YongjingGuo2?,KlementyShchetynsky1,AndrewHill3,MohsenKhademi4,TomasOlsson4,
PadmalathaSReddy3,MariaSeddighzadeh1,JamesDClark2,Lih-LingLin2,MargotO’Toole2and
LeonidPadyukov1
Abstract
Background:TheR620Wvariantinproteintyrosinephosphatasenon-receptor22(PTPN22)isassociatedwith
rheumatoidarthritis(RA).ThePTPN22genehasalternativelysplicedtranscriptsandatleasttwoofthespliceforms
havebeenconfir
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