The efficacy of Link N as a mediator of repair in a rabbit model of intervertebral disc degeneration 英文参考文献.docVIP

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The efficacy of Link N as a mediator of repair in a rabbit model of intervertebral disc degeneration 英文参考文献.doc

The efficacy of Link N as a mediator of repair in a rabbit model of intervertebral disc degeneration 英文参考文献

Mwaleetal.ArthritisResearchTherapy2011,13:R120 /content/13/4/R120 RESEARCH ARTICLE OpenAccess TheefficacyofLinkNasamediatorofrepairina rabbitmodelofintervertebraldiscdegeneration FacksonMwale1,2*,KoichiMasuda3,RajeswariPichika3,LauraMEpure2,TomoakiYoshikawa3,AseemHemmad3, PeterJRoughley4andJohnAntoniou1,2 Abstract Introduction:Intervertebraldisc(IVD)degenerationisassociatedwithproteolyticdegradationoftheextracellular matrix,anditsrepairrequiresboththeproductionofextracellularmatrixandthedownregulationofproteinase activity.Thesepropertiesareassociatedwithseveralgrowthfactors.However,theuseof

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