The involvement of interleukin-1 and interleukin-4 in the response of human annulus fibrosus cells to cyclic tensile strain an altered mechanotransduction pathway with degeneration 英文参考文献.docVIP

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The involvement of interleukin-1 and interleukin-4 in the response of human annulus fibrosus cells to cyclic tensile strain an altered mechanotransduction pathway with degeneration 英文参考文献.doc

The involvement of interleukin-1 and interleukin-4 in the response of human annulus fibrosus cells to cyclic tensile strain an altered mechanotransduction pathway with degeneration 英文参考文献

Gilbertetal.ArthritisResearchTherapy2011,13:R8 /content/13/1/R8 RESEARCH ARTICLE OpenAccess Theinvolvementofinterleukin-1andinterleukin-4 intheresponseofhumanannulusfibrosuscellsto cyclictensilestrain:analtered mechanotransductionpathwaywithdegeneration HamishTJGilbert,JudithAHoyland,AnthonyJFreemont,SarahJMillward-Sadler* Abstract Introduction:Recentevidencesuggeststhatintervertebraldisc(IVD)cellsderivedfromdegenerativetissueare unabletorespondtophysiologicallyrelevantmechanicalstimuliinthe‘normal’anabolicmanner,butinstead respondbyincreasingmatrixcatabolism.Understandingthenatureofthebiol

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The involvement of interleukin-1 and interleukin-4 in the response of human annulus fibrosus cells to cyclic tensile strain an altered mechanotransduction pathway with degeneration 英文参考文献.docVIP