七年制如何做好科研.pptVIP

七年制学生如何做好科研 口腔医学院/医院 张旭 * What, How, Why What is research? How do we do research? Why do we do research? Who, How, Why Who are you? How do you like dentistry? Why do you choose dentistry? * The Rationale of CPP-ACP CPP-ACP CPP-ACP can localize in dental plaque and then release Ca2+ and PO43- , which forms a supersaturation environment on tooth surface with respect to HAP to facilitate remineralization. What is research? Limitations Your hypothesis What are others doing/What have others done? How are they doing/How did they do? Topic (Why do others do this?) How do we do research? * CPP Nano-complex ACP Abundant Phosphate group trapping more calcium ions to form CPP-ACP nano-complex P O Ca2+ Ca2+ Ca2+ O- -O O- A Nano-complex of Amorphous Calcium Phosphate (ACP) Stablized by Casein Phosphopeptides(CPP) Recaldent (CPP-ACP nanocomplexes): a protein technology * The Rationale of CPP-ACP CPP-ACP CPP-ACP can localize in dental plaque and then release Ca2+ and PO43- , which forms a supersaturation environment on tooth surface with respect to HAP to facilitate remineralization. * The Limitations of CPP-ACP and Its Science Inspiration The Limitations: (1) Unsuitable for person allergic to milk; (2) Lack of anti-bacterial ability; (3) Relatively high-priced compared with normal toothpastes; (4) Foreign intellectual property. The Science Inspiration: Pazit et al. 2004 Development of a new remineralizing agent: To find a non-toxic and biocompatible polyelectrolyte to stablize amorphous calcium phosphate. * What is research paper? Introduction Methods and Materials Results Discussion Language Attitude is a little thing that make big difference. Imitate Dictionary Repeat Why do we do research? * *