Treatment patterns and clinical characteristics prior to initiating depot typical antipsychotics for nonadherent schizophrenia patients 英文参考文献.docVIP

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Treatment patterns and clinical characteristics prior to initiating depot typical antipsychotics for nonadherent schizophrenia patients 英文参考文献.doc

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Treatment patterns and clinical characteristics prior to initiating depot typical antipsychotics for nonadherent schizophrenia patients 英文参考文献

BMC Psychiatry BioMedCentral Research article Open Access Treatment patterns and clinical characteristics prior to initiating depot typical antipsychotics for nonadherent schizophrenia patients Haya Ascher-Svanum*1, Xiaomei Peng2, Douglas Faries2, William Montgomery3 and Peter M Haddad4,5 Address: 1Eli Lilly and Company, Indianapolis, IN, USA, 2Lilly USA, LLC, Indianapolis, IN, USA, 3Eli Lilly Australia Pty Ltd, Macquarie Park, Australia, 4Greater Manchester West Mental Health NHS Foundation Trust, Manchester, UK and 5Neuroscience and Psychiatry Unit, School of Psychiatry and Behavioural Sciences, University of Manchester, Manchester, UK Email: Haya Ascher-Svanum* - haya@; Xiaomei Peng - x_peng@; Douglas Faries - d.faries@; William Montgomery - Montgomery_bill@; Peter M Haddad - peterhaddad@.uk * Corresponding author Published: 29 July 2009 Received: 1 December 2008 Accepted: 29 July 2009 BMC Psychiatry 2009, 9:46 doi:10.1186/1471-244X-9-46 This article is available from: /1471-244X/9/46 ? 2009 Ascher-Svanum et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Background: Nonadherence with antipsychotic medication is an important clinical and economic problem in the treatment of schizophrenia. This study identified treatment patterns and clinical characteristics that immediately precede the initiation of depot typical antipsychotics in the usual treatment of schizophrenia patients with a recent history of nonadherence with oral antipsychotic regimens. Methods: Data were drawn from a large, multisite, 3-year prospective noninterventional observational study of persons treated for schizophrenia in the United States, which was conducted between 7/1997 and 9/2003. The analytical sample included patients who,