Usual interstitial pneumonia coexisted with nonspecific interstitial pneumonia, What’s the diagnosis 英文参考文献.docVIP

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Usual interstitial pneumonia coexisted with nonspecific interstitial pneumonia, What’s the diagnosis 英文参考文献.doc

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Usual interstitial pneumonia coexisted with nonspecific interstitial pneumonia, What’s the diagnosis 英文参考文献

Fangetal.DiagnosticPathology2012,7:167 /content/7/1/167 CASE REPORT OpenAccess Usualinterstitialpneumoniacoexistedwith nonspecificinterstitialpneumonia,What’ sthe diagnosis? XiaFang1,BenfangLuo3,XianghuaYi1*,YuZeng1,FangLiu1,HuipingLi2,PanGu1,XuyouZhu1,SuxiaZhang1 andGelinJiang2 Abstract Thedifferentialdiagnosisbetweenidiopathicnonspecificinterstitialpneumonia(INSIP)andidiopathicpulmonary fibrosis(IPF)/usualinterstitialpneumonia(UIP)istoughinbothcliniciansandpathologists.Inthisstudy,weanalyzed thelesionsofrightlungremovedfroma58-year-oldpatientbygrossandmicroscopy.Theresultsshowedthatthe pathologicalappearanceofnonspecificinterstitialpneumonia(NSIP)andUIPcoexistedinhisupperlobe.Besides, becauseofseverefibrosisinmiddleandlowerlobes,itwashardtodistinguishthelesionsofNSIPfibroticpattern (NSIP-F)orUIP.Basedonclinic-radiologic-pathologicaldata,thediagnosisofINSIP-Fwasmadeforthispatient finally.OurstudysuggeststhatUIPisnotalwaysanaccuratediagnosiswhentheNSIPandUIPcoexist,andNSIP canhaveregionsofUIP. Virtualslide:Thevirtualslide(s)forthisarticlecanbefoundhere:http://www.diagnosticpathology.diagnomx.eu/vs/ 2573531681608730 Keywords:Nonspecificinterstitialpneumonia,Usualinterstitialpneumonia,Idiopathicnonspecificinterstitial pneumonia,Diagnosis Background inwhichUIPpatternexistedwithNSIP;thesamplewasa Because of different treatment and prognosis for idio- wholerightlungremovedfrompneumonectomy. pathic nonspecific interstitial pneumonia(INSIP) and idiopathic pulmonary fibrosis (IPF) / usual interstitial pneumonia (UIP), accurate diagnosis for this two dis- Casepresentation eases become critical for clinicians and pathologists Here’sa58-year-oldmanwithahistoryofsmokingwith- [1-3].However,thedifferentialdiagnosisamongthemis out dust and poisons contact, who came to Shanghai hard for both clinicians and pathologists [4], especially Pulmonary Hospital in July 2004 because of repeated between INSIP fibrotic pattern (INSIP-F) and IPF/UIP. cough, expectoration and progre