A phenotypic screening platform to identify small molecule modulators of Chlamydomonas reinhardtii growth, motility and photosynthesis.docVIP

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A phenotypic screening platform to identify small molecule modulators of Chlamydomonas reinhardtii growth, motility and photosynthesis.doc

A phenotypic screening platform to identify small molecule modulators of Chlamydomonas reinhardtii growth, motility and photosynthesis

Alfredetal.GenomeBiology2012,13:R105 /2012/13/11/R105 METHOD OpenAccess Aphenotypicscreeningplatformtoidentifysmall moleculemodulatorsofChlamydomonas reinhardtiigrowth,motilityandphotosynthesis SimonEAlfred1,2,3,AnuradhaSurendra1,2,4,ChrisLe1,KenLin1,AlexanderMok1,IainMWallace1,6,MichaelProctor5, MaleneLUrbanus1,4,GuriGiaever1,3,4 andCoreyNislow1,2,3* Abstract Chemicalbiology,theinterfacialdisciplineofusingsmallmoleculesasprobestoinvestigatebiology,isapowerful approachofdevelopingspecific,rapidlyactingtoolsthatcanbeappliedacrossorganisms.Thesingle-celledalga Chlamydomonasreinhardtiiisanexc

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A phenotypic screening platform to identify small molecule modulators of Chlamydomonas reinhardtii growth, motility and photosynthesis.docVIP