A positive serum basophil histamine release assay is a marker for ciclosporin-responsiveness in patients with chronic spontaneous urticaria.docVIP
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A positive serum basophil histamine release assay is a marker for ciclosporin-responsiveness in patients with chronic spontaneous urticaria
Iqbaletal.ClinicalandTranslationalAllergy2012,2:19
/content/2/1/19
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OpenAccess
Apositiveserumbasophilhistaminereleaseassay
isamarkerforciclosporin-responsivenessin
patientswithchronicspontaneousurticaria
KamranIqbal1,KapilBhargava1,PerStahlSkov2,SidselFalkencrone2andCliveEHGrattan1*
Abstract
Theelectronicrecordsof398patientswithchronicspontaneousurticaria(CSU)whohadhadaserumbasophil
histaminereleaseassay(BHRA)performedasamarkeroffunctionalautoantibodieswereaudited.TheBHRAwas
positivein105patients(26.4%).FiftyeightweretreatedwithciclosporinbecausetheywereH1anti-histamine
un
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