A sex-specific association of common variants of neuroligin genes (NLGN3 and NLGN4X) with autism spectrum disorders in a Chinese Han cohort.docVIP
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A sex-specific association of common variants of neuroligin genes (NLGN3 and NLGN4X) with autism spectrum disorders in a Chinese Han cohort
Yuetal.BehavioralandBrainFunctions2011,7:13
/content/7/1/13
RESEARCH
OpenAccess
Asex-specificassociationofcommonvariantsof
neuroligingenes(NLGN3andNLGN4X )with
autismspectrumdisordersinaChineseHan
cohort
JindanYu1,XueHe1,DanYao1,ZhongyueLi2,HuiLi3andZhengyanZhao1*
Abstract
Background:Synapticgenes,NLGN3andNLGN4X,twohomologousmembersoftheneuroliginfamily,havebeen
supposedaspredispositionlociforautismspectrumdisorders(ASDs),anddefectsofthesetwogeneshavebeen
identifiedinasmallfractionofindividualswithASDs.Butnosuchrarevariantinthesetwogeneshasasyetbeen
adequatelyreplicatedinChinesepopulationand
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