A sex-specific association of common variants of neuroligin genes (NLGN3 and NLGN4X) with autism spectrum disorders in a Chinese Han cohort.docVIP

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A sex-specific association of common variants of neuroligin genes (NLGN3 and NLGN4X) with autism spectrum disorders in a Chinese Han cohort.doc

A sex-specific association of common variants of neuroligin genes (NLGN3 and NLGN4X) with autism spectrum disorders in a Chinese Han cohort

Yuetal.BehavioralandBrainFunctions2011,7:13 /content/7/1/13 RESEARCH OpenAccess Asex-specificassociationofcommonvariantsof neuroligingenes(NLGN3andNLGN4X )with autismspectrumdisordersinaChineseHan cohort JindanYu1,XueHe1,DanYao1,ZhongyueLi2,HuiLi3andZhengyanZhao1* Abstract Background:Synapticgenes,NLGN3andNLGN4X,twohomologousmembersoftheneuroliginfamily,havebeen supposedaspredispositionlociforautismspectrumdisorders(ASDs),anddefectsofthesetwogeneshavebeen identifiedinasmallfractionofindividualswithASDs.Butnosuchrarevariantinthesetwogeneshasasyetbeen adequatelyreplicatedinChinesepopulationand

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