原创力文档ABCG2 is associated with HER-2 Expression, lymph node metastasis and clinical stage in breast invasive ductal carcinoma.docVIP
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ABCG2 is associated with HER-2 Expression, lymph node metastasis and clinical stage in breast invasive ductal carcinoma
Xiangetal.DiagnosticPathology2011,6:90
/content/6/1/90
RESEARCH
OpenAccess
ABCG2isassociatedwithHER-2Expression,
lymphnodemetastasisandclinicalstagein
breastinvasiveductalcarcinoma
LeiXiang,PengSu,ShujunXia,ZhiyanLiu,YanWang,PengGaoandGenyinZhou*
Abstract
Background:ABCG2isanABCtransporter.IthasbeendemonstratedthatendogenousABCG2expressionin
certaincancersisapossiblereflectionofthedifferentiatedphenotypeofthecelloforiginandlikelycontributesto
intrinsicdrugresistance.ButlittleisknownaboutthecontributionofABCG2tothedrugresistanceandthe
clinicopathologicalcharacteristicsinbreastcancer.Inthepresen
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