Ageing, autoimmunity and arthritis T-cell senescence and contraction of T-cell repertoire diversity – catalysts of autoimmunity and chronic inflammation.docVIP

Available online /content/5/5/225 Review Ageing, autoimmunity and arthritis T-cell senescence and contraction of T-cell repertoire diversity – catalysts of autoimmunity and chronic inflammation J?rg J Goronzy1,2 and Cornelia M Weyand1,2 1Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA 2Department of Immunology, Mayo Clinic, Rochester, Minnesota, USA Correspondence: J?rg J Goronzy (e-mail: goronzy.jorg@) Received: 8 May 2003 Revisions requested: 25 Jun 2003 Revisions received: 21 Jul 2003 Accepted: 24 Jul 2003 Published: 8 Aug 2003 Arthritis Res Ther 2003, 5:225