Associations between a neurophysiological marker of central cholinergic activity and cognitive functions in young and older adults.docVIP
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Associations between a neurophysiological marker of central cholinergic activity and cognitive functions in young and older adults
Young-Bernieretal.BehavioralandBrainFunctions2012,8:17
/content/8/1/17
RESEARCH
OpenAccess
Associationsbetweenaneurophysiological
markerofcentralcholinergicactivityand
cognitivefunctionsinyoungandolderadults
MarielleYoung-Bernier1,2,YaelKamil1,Fran?oisTremblay1,2,3andPatrickSRDavidson1,2,4*
Abstract
Background:Thedeteriorationofthecentralcholinergicsysteminagingishypothesizedtounderliedeclinesin
severalcognitivedomains,includingmemoryandexecutivefunctions.However,thereissurprisinglylittledirect
evidenceregardingacetylcholine’sspecificrole(s)innormalhumancognitiveaging.
Methods:Weusedshort-la
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