Associations between the HLA-A polymorphism and the clinical manifestations of Behcets disease.docVIP

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Associations between the HLA-A polymorphism and the clinical manifestations of Behcets disease.doc

Associations between the HLA-A polymorphism and the clinical manifestations of Behcets disease

Kangetal.ArthritisResearchTherapy2011,13:R49 /content/13/2/R49 RESEARCH ARTICLE OpenAccess AssociationsbetweentheHLA-Apolymorphism andtheclinicalmanifestationsofBehcet’ sdisease EunHaKang1?,JeongYeonKim2?,FujioTakeuchi3,JoonWanKim2,KichulShin2,EunYoungLee2,YunJongLee1, EunBongLee2,4,MyoungHeePark4,5 andYeongWookSong2,4* Abstract Introduction:TheobjectivewastoinvestigateassociationsbetweentheHLA-AgeneandBehcet’sdisease(BD) anditsclinicalmanifestations. Methods:GenotypingfortheHLA-Alocuswasperformedusingthepolymerasechainreaction-Luminextyping methodin223BDpatientsand1,398healthycontrols. R

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