Asymmetric Synthesis of the Epimeric (3S)-3-((E)-Hex-1-enyl)-2-methylcyclohexanones.docVIP

Molecules 2007, 12, 237-244 molecules ISSN 1420-3049 Full Paper Asymmetric Synthesis of the Epimeric (3S)-3-((E)-Hex-1-enyl)- 2-methylcyclohexanones Freek A. Vrielynck and Pierre J. De Clercq* Ghent University, Department of Organic Chemistry, Laboratory for Organic Synthesis, Krijgslaan 281 (S4), B-9000 Gent, Belgium * Author to whom correspondence should be addressed. E-mail: pierre.declercq@UGent.be Received: 9 January 2007; in revised form: 20 February 2007 / Accepted: 20 February 2007 / Published: 21 February 2007 Abstract: The asymmetric rhodium-catalysed 1,4-addition of alkenylzirco