Bacterial flagellin elicits widespread innate immune defense mechanisms, apoptotic signaling, and a sepsis-like systemic inflammatory response in mice.docVIP

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Bacterial flagellin elicits widespread innate immune defense mechanisms, apoptotic signaling, and a sepsis-like systemic inflammatory response in mice.doc

Bacterial flagellin elicits widespread innate immune defense mechanisms, apoptotic signaling, and a sepsis-like systemic inflammatory response in mice

Rollietal.CriticalCare2010,14:R160 /content/14/4/R160 RESEARCH OpenAccess Bacterialflagellinelicitswidespreadinnate immunedefensemechanisms,apoptotic signaling,andasepsis-likesystemicinflammatory responseinmice Jo?lleRolli1,NoureddineLoukili1,SandraLevrand1,NathalieRosenblatt-Velin2,StéphanieRignault-Clerc2, BernardWaeber2,Fran?oisFeihl2,PalPacher3,LucasLiaudet1* Abstract Introduction:Systemicinflammationinsepsisisinitiatedbyinteractionsbetweenpathogenmolecularmotifsand specifichostreceptors,especiallytoll-likereceptors(TLRs).Flagellinisthemainflagellarproteinofmotile microorganismsandisthel

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Bacterial flagellin elicits widespread innate immune defense mechanisms, apoptotic signaling, and a sepsis-like systemic inflammatory response in mice.docVIP