Baicalein antagonizes rotenone-induced apoptosis in dopaminergic SH-SY5Y cells related to Parkinsonism.docVIP
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Baicalein antagonizes rotenone-induced apoptosis in dopaminergic SH-SY5Y cells related to Parkinsonism
Songetal.ChineseMedicine2012,7:1
/content/7/1/1
RESEARCH
OpenAccess
Baicaleinantagonizesrotenone-induced
apoptosisindopaminergicSH-SY5Ycellsrelated
toParkinsonism
Ju-XianSong1,MandyYuen-ManChoi1,KavinChun-KitWong1,WinkieWing-YanChung1,StephenCho-WingSze1,
Tzi-BunNg2andKalinYan-BoZhang1*
Abstract
Background:Twoactivecompounds,baicaleinanditsglycosidebaicalinwerefoundinthedriedrootof
ScutellariabaicalensisGeorgi,andreportedtobeneuroprotectiveinvitroandinvivo.Thisstudyaimstoevaluate
theprotectiveeffectsofbaicaleinontherotenone-inducedapoptosisindopaminergicSH-SY5Ycellsrelatedto
parkinsonism.
Me
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