原创力文档Bone resorption and remodeling in murine collagenase-induced osteoarthritis after administration of glucosamine.docVIP
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Bone resorption and remodeling in murine collagenase-induced osteoarthritis after administration of glucosamine
IvanovskaandDimitrovaArthritisResearchTherapy2011,13:R44
/content/13/2/R44
RESEARCH ARTICLE
OpenAccess
Boneresorptionandremodelinginmurine
collagenase-inducedosteoarthritisafter
administrationofglucosamine
NinaIvanovska,PetyaDimitrova*
Abstract
Introduction:Glucosamineisanamino-monosaccharideandprecursorofglycosaminoglycans,majorcomponents
ofjointcartilage.Glucosaminehasbeenclinicallyintroducedforthetreatmentofosteoarthritisbutthedataabout
itsprotectiveroleindiseaseareinsufficient.Thegoalofthisstudywastoinvestigatetheeffectoflongterm
administrationofglucosamineonboneresorptionandremodeling.
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