Canonical Modeling of the Multi-Scale Regulation of the Heat Stress Response in Yeast.docVIP

Metabolites 2012, 2, 221-241; doi:10.3390/metabo2010221 OPEN ACCESS metabolites ISSN 2218-1989 /journal/metabolites/ Article Canonical Modeling of the Multi-Scale Regulation of the Heat Stress Response in Yeast Luis L. Fonseca 1,2, Po-Wei Chen 2 and Eberhard O. Voit 2,* 1 Instituto de Tecnologia Qu?ímica e Biológica, Universidade Nova de Lisboa / Av. da República, Esta??o Agronómica Nacional, 2780-157 Oeiras, Portugal; E-Mail: llf@itqb.unl.pt 2 Integrative BioSystems Institute and The Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology, 313 Ferst Drive,