贫血及贫血性心脏病-夜课件.pptVIP

Anemia AND Anemia Heart Disease 本文档由医学百事通高端医生网专家制作 在线咨询医生网址: Definition Anemia is defined as a decrease in the circulating RBC, hemoglobin or the hematocrit ,and a corresponding decrease in the oxygen-carrying capacity of the blood. Normal values of the hemogram (In sea level): TEST WOMEN MEN HCT (%) 37-48 40-50 Hb (g/L) 110-150 120-160 RBC Count(1012/L) 3.5-5.0 4.0-5.5 Diagnosis WOMEN MEN PREGNANT Diagnosis First step : detection of the presence of anemia,and the severity. Second step: laboratory investigation of the morphological classification. Third step: investigation of the pathogenesis of anemia. Diagnosis Diagnosis cell morphological type MCV（fl） MCH(pg) MCHC (%) Macrocytic anemia 100 34 32～36 Normocytic anemia 80～100 27 ～34 32～36 Microcytic hypochromic anemia Simple microcytic anemia Diagnosis Third step: according to etiology/pathogenesis 1.Blood loss--acute hemorrhage chronic hemorrhage 2. Increased RBC destruction --hemolytic anemia(HA) Diagnosis RBC internal defect (1)RBC membrane defect acquired: PNH hereditary : hereditary spherocytosis (2) enzyme deficiency: G6PD deficiency (3) Hb abnormality: hemoglobinopathy, Thalassemia (4) porphyrin metabolism : porphyrinopathy Exopathic immunologic (AIHA), chemical, biological, or phisical factors Diagnosis 3. Decresed RBC production Diagnosis Complete diagnosis 1. Anemia 2. Degree of anemia 3. Clas