Changes of monocyte human leukocyte antigen-DR expression as a reliable predictor of mortality in severe sepsis.docVIP

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Changes of monocyte human leukocyte antigen-DR expression as a reliable predictor of mortality in severe sepsis.doc

Changes of monocyte human leukocyte antigen-DR expression as a reliable predictor of mortality in severe sepsis

Wuetal.CriticalCare2011,15:R220 /content/15/5/R220 RESEARCH OpenAccess Changesofmonocytehumanleukocyteantigen- DRexpressionasareliablepredictorofmortality inseveresepsis Jian-FengWu1?,JieMa1?,JuanChen1,BinOu-Yang1,Min-YingChen1,Li-FenLi1,Yong-JunLiu1,Ai-HuaLin2and Xiang-DongGuan1* Abstract Introduction:Manystudieshaveshownthatmonocytehumanleukocyteantigen-DR(mHLA-DR)expressionmay beagoodpredictorformortalityinseveresepticpatients.Onthecontrary,otherstudiesfoundmHLA-DRwasnot ausefulprognosticmarkerinseveresepsis.FewstudieshavetakenchangesofmHLA-DRduringtreatmentinto consideration.Theobjective

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