Changes of monocyte human leukocyte antigen-DR expression as a reliable predictor of mortality in severe sepsis.docVIP
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Changes of monocyte human leukocyte antigen-DR expression as a reliable predictor of mortality in severe sepsis
Wuetal.CriticalCare2011,15:R220
/content/15/5/R220
RESEARCH
OpenAccess
Changesofmonocytehumanleukocyteantigen-
DRexpressionasareliablepredictorofmortality
inseveresepsis
Jian-FengWu1?,JieMa1?,JuanChen1,BinOu-Yang1,Min-YingChen1,Li-FenLi1,Yong-JunLiu1,Ai-HuaLin2and
Xiang-DongGuan1*
Abstract
Introduction:Manystudieshaveshownthatmonocytehumanleukocyteantigen-DR(mHLA-DR)expressionmay
beagoodpredictorformortalityinseveresepticpatients.Onthecontrary,otherstudiesfoundmHLA-DRwasnot
ausefulprognosticmarkerinseveresepsis.FewstudieshavetakenchangesofmHLA-DRduringtreatmentinto
consideration.Theobjective
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