Characterization of monocytemacrophage subsets in the skin and peripheral blood derived from patients with systemic sclerosis.docVIP

Higashi-Kuwata et al. Arthritis Research Therapy 2010, 12:R128 /content/12/4/R128 RESEARCH ARTICLE Open Access Characterization of monocyte/macrophage Research article subsets in the skin and peripheral blood derived from patients with systemic sclerosis Nobuyo Higashi-Kuwata1, Masatoshi Jinnin*1, Takamitsu Makino1, Satoshi Fukushima1, Yuji Inoue1, Faith C Muchemwa1, Yuji Yonemura2, Yoshihiro Komohara3, Motohiro Takeya3, Hiroaki Mitsuya4,5 and Hironobu Ihn1 Abstract Introduction: Recent accumulating evidence indicates a crucial involvement of macrophage lineage in the pathogenesis of