Characterization of the quinolone resistant determining regions in clinical isolates of pneumococci collected in Canada.docVIP

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Characterization of the quinolone resistant determining regions in clinical isolates of pneumococci collected in Canada.doc

Characterization of the quinolone resistant determining regions in clinical isolates of pneumococci collected in Canada

Pateletal.AnnalsofClinicalMicrobiologyandAntimicrobials2010,9:3 /content/9/1/3 RESEARCH OpenAccess Characterizationofthequinoloneresistant determiningregionsinclinicalisolatesof pneumococcicollectedinCanada SamirNPatel1,2,3,RobertoMelano1,2,3,AllisonMcGeer1,2,KarenGreen2,DonaldELow1,2,3* Abstract Background:TheobjectiveofthisstudywastoexamineStreptococcuspneumoniaeisolatescollectedfroma longitudinalsurveillanceprograminordertodeterminetheirsusceptibilitytocurrentlyusedfluoroquinolonesand ofthefrequencyandtypeofmutationsinthequinolone-resistantdeterminingregions(QRDRs)oftheirparCand gyrAgenes.

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