Chemical genomics in yeast.docVIP

Minireview Chemical genomics in yeast Charles Brenner Address: Departments of Genetics and Biochemistry and the Norris Cotton Cancer Center, Dartmouth Medical School, Lebanon, NH 03756, USA. E-mail: charles.brenner@ Published: 27 August 2004 Genome Biology 2004, 5:240 The electronic version of this article is the complete one and can be found online at /2004/5/9/240 ? 2004 BioMed Central Ltd Abstract Many drugs have unknown, controversial or multiple mechanisms of action. Four recent ‘chemical genomic’ studies, using genome-scale collections of yeast gene deletions that were either ar