Chemical Synthesis, Backbone Cyclization and Oxidative Folding of Cystine-knot Peptides — Promising Scaffolds for Applications in Drug Design.docVIP

Molecules 2012, 17, 12533-12552; doi:10.3390/molecules171112533 OPEN ACCESS molecules ISSN 1420-3049 /journal/molecules Review Chemical Synthesis, Backbone Cyclization and Oxidative Folding of Cystine-knot Peptides — Promising Scaffolds for Applications in Drug Design Michael Reinwarth ?, Daichi Nasu ?, Harald Kolmar and Olga Avrutina * Institute for Organic Chemistry and Biochemistry, Technische Universit?t Darmstadt, Petersenstra?e 22, D-64287 Darmstadt, Germany ? These authors contributed equally to this work. * Author to whom correspondence should be addressed; E-Mail: Avrutina@Bioch